Miejsce diuretyków pętlowych w leczeniu ostrej niewydolności serca

Loop diuretics are used as first-line medications in patients with heart failure they result symptomatic improvement related to relieving organ congestion. The recommendations regarding the use of loop mostly based on expert opinion, without preference specific drugs. Thus, choice optimal diuretic treatment strategy acute heart requires knowledge about differences characteristics available Poland, furosemide and torasemide. Non-renal pleiotropic effects torasemide should be also borne mind. Clinically significant differences pharmacokinetics and biological furosemide have been reflected multiple research studies meta-analyses published recent several years. These provided consistent evidence for good safety profile torasemide, its superior efficacy regard improvement exercise tolerance reduced readmissions due compared furosemide. effect on mortality reduction failure, seen some studies, further evaluation.